A paper that analysed genetic variants in 14,000 people to identify disease-associated regions set the standard for collaborative genome-wide association studies and provided methodological advances whose effects are still felt today.
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References
The Wellcome Trust Case Control Consortium. Nature 447, 661–678 (2007).
Hirschhorn, J. N., Lohmueller, K., Byrne, E. & Hirschhorn, K. Genet. Med. 4, 45–61 (2002).
Klein, R. J. et al. Science 308, 385–389 (2005).
Hindorff, L. A. et al. Proc. Natl Acad. Sci. USA 106, 9362–9367 (2009).
Manolio, T. A., Brooks, L. D. & Collins, F. C. J. Clin. Invest. 118, 1590–1605 (2008).
Mossman, K. Sci. Am. 298, 42 (2008).
Summerskill, W. Lancet 371, 370–371 (2008).
Warren, H. R. et al. Nature Genet. 49, 403–415 (2017).
Marchini, J., Howie, B., Myers, S., McVean, G. & Donnelly, P. Nature Genet. 39, 906–913 (2007).
Homer, N. et al. PLoS Genet. 4, e1000167 (2008).
Popejoy, A. B. & Fullerton, S. M. Nature 538, 161–164 (2016).
Evans, D. S. et al. Hum. Mol. Genet. 25, 4350–4368 (2016).
Cade, B. E. et al. Am. J. Respir. Crit. Care Med. 194, 886–897 (2016).
Chan, S. L., Jin, S., Loh, M. & Brunham, L. R. Pharmacogenomics 16, 1161–1178 (2015).
Price, A. L., Spencer, C. C. A. & Donnelly, P. Proc. R. Soc. B 282, 20151684 (2015).
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Manolio, T. A decade of shared genomic associations. Nature 546, 360–361 (2017). https://doi.org/10.1038/546360a
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DOI: https://doi.org/10.1038/546360a
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