A catalyst that couples together three reactants to form just one compound out of several possibilities, as a single mirror-image isomer, should simplify the synthesis of biologically relevant molecules. See Article p.367
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References
Meng, F., McGrath, K. P. & Hoveyda, A. H. Nature 513, 367–374 (2014).
Keasling, J. D., Mendoza, A. & Baran, P. S. Nature 492, 188–189 (2012).
de Graaff, C., Ruijter, E. & Orru, R. V. A. Chem. Soc. Rev. 41, 3969–4009 (2012).
Joule, J. A. & Mills, K. Heterocyclic Chemistry 5th edn (Blackwell, 2010).
Noyori, R. Asymmetric Catalysis in Organic Synthesis (Wiley, 1994).
Meng, F., Jang, H., Jung, B. & Hoveyda, A. H. Angew. Chem. Int. Edn 52, 5046–5051 (2013).
Czuba, I. R., Zammit, S. & Rizzacasa, M. A. Org. Biomol. Chem. 1, 2044–2056 (2003).
Kuttruff, C. A., Eastgate, M. D. & Baran, P. S. Nat. Prod. Rep. 31, 419–432 (2014).
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Villaume, M., Baran, P. Reactivity tamed one bond at a time. Nature 513, 324–325 (2014). https://doi.org/10.1038/513324a
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DOI: https://doi.org/10.1038/513324a