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Cancer

Mutations close in on gene regulation

A genome-wide analysis of DNA and RNA sequences, gene expression and DNA modifications in 200 samples of acute myeloid leukaemia sets the stage for data integration and verification that will enhance our understanding of this cancer.

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Figure 1: Frequent mutations in acute myeloid leukaemia.

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Correspondence to Stein Aerts or Jan Cools.

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Aerts, S., Cools, J. Mutations close in on gene regulation. Nature 499, 35–36 (2013). https://doi.org/10.1038/499035a

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