Drugs used to treat African sleeping sickness are outdated, and how they enter cells and exert biological effects is poorly understood. A genome-wide study using RNA interference provides valuable insight. See Letter p.232
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Fairlamb, A. Genomics decodes drug action. Nature 482, 167–169 (2012). https://doi.org/10.1038/482167a
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DOI: https://doi.org/10.1038/482167a