The synthesis of conolidine, a scarce, naturally occurring compound, has enabled the first studies of its pharmacological properties to be carried out. Excitingly, conolidine is a painkiller that seems to have an unusual mechanism of action.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Tarselli, M. A. et al. Nature Chem. 3, 449–453 (2011).
Kam, T.-S., Pang, H.-S., Choo, Y.-M. & Komiyama, K. Chem. Biodiver. 1, 646–656 (2004).
Potier, P. & Janot, M. M. C.R. Acad. Sci. 276C, 1727 (1973).
Scott, A. I., Yeh, C.-L. & Greenslade, D. J. Chem. Soc. Chem. Commun. 947–948 (1978).
Rice, K. C. in The Chemistry and Biology of Isoquinoline Alkaloids (eds Phillipson, J. D., Roberts, M. F. & Zenk, M. H.) 191–203 (Springer, 1985).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Reisman, S. New lead for pain treatment. Nature 473, 458–459 (2011). https://doi.org/10.1038/473458a
Published:
Issue Date:
DOI: https://doi.org/10.1038/473458a