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Chemical biology

Catalytic detoxification

Protein engineering of an enzyme that catalytically detoxifies organophosphate compounds in the body opens up fresh opportunities in the search for therapeutic protection against nerve agents used in chemical warfare.

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Figure 1: Enzyme reactions of organophosphate nerve agents.

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Raushel, F. Catalytic detoxification. Nature 469, 310–311 (2011). https://doi.org/10.1038/469310a

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