Resistance of tumour cells to chemotherapy can severely affect the efficacy of this anticancer treatment. The non-tumour cells of the organ in which the tumour resides may aid the emergence of such resistance.
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R.S.K. is a consultant to Taiho and GSK Pharmaceuticals for metronomic chemotherapy, and is a recipient of sponsored research agreements from Pfizer and GSK to study small-molecule antiangiogenic receptor tyrosine kinase antagonists.
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Emmenegger, U., Kerbel, R. Chemotherapy counteracted. Nature 468, 637–638 (2010). https://doi.org/10.1038/468637a
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DOI: https://doi.org/10.1038/468637a
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