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Cancer

Chemotherapy counteracted

Resistance of tumour cells to chemotherapy can severely affect the efficacy of this anticancer treatment. The non-tumour cells of the organ in which the tumour resides may aid the emergence of such resistance.

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Figure 1: Endothelial stress response and chemoresistance.

References

  1. Pang, R. et al. Cell Stem Cell 6, 603–615 (2010).

    Article  CAS  Google Scholar 

  2. Gilbert, L. A. & Hemann, M. T. Cell 143, 355–366 (2010).

    Article  CAS  Google Scholar 

  3. Butler, J. M., Kobayashi, H. & Rafii, S. Nature Rev. Cancer 10, 138–146 (2010).

    Article  CAS  Google Scholar 

  4. Kerbel, R. S. & Ebos, J. M. L. Nature Med. 16, 1084–1085 (2010).

    Article  CAS  Google Scholar 

  5. Wang, Y. et al. Cancer Lett. 295, 110–123 (2010).

    Article  CAS  Google Scholar 

  6. Nie, D. Front. Biosci. (Schol. Edn) 2, 184–193 (2010).

    Article  Google Scholar 

  7. Pusztai, L. et al. Cytokine 25, 94–102 (2004).

    Article  CAS  Google Scholar 

  8. Pasquier, E., Kavallaris, M. & André, N. Nature Rev. Clin. Oncol. 7, 455–465 (2010).

    Article  Google Scholar 

  9. Rodier, F. et al. Nature Cell Biol. 11, 973–979 (2009).

    Article  CAS  Google Scholar 

  10. Dorff, T. B. et al. Clin. Cancer Res. 16, 3028–3034 (2010).

    Article  CAS  Google Scholar 

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Competing interests

R.S.K. is a consultant to Taiho and GSK Pharmaceuticals for metronomic chemotherapy, and is a recipient of sponsored research agreements from Pfizer and GSK to study small-molecule antiangiogenic receptor tyrosine kinase antagonists.

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Emmenegger, U., Kerbel, R. Chemotherapy counteracted. Nature 468, 637–638 (2010). https://doi.org/10.1038/468637a

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