Protein factors can regulate gene expression by binding to specifically modified DNA-associated proteins. Small molecules that selectively interfere with such interaction may be of therapeutic value. See Article p.1067 & Letter p.1119
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Taverna, S., Cole, P. Reader's block. Nature 468, 1050–1051 (2010). https://doi.org/10.1038/4681050a
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DOI: https://doi.org/10.1038/4681050a
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Cytotoxic activity of bromodomain inhibitor NVS-CECR2-1 on human cancer cells
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