Your discussion of sex bias in biomedical research (Nature 465, 665; 2010 and Nature 465 688–690; 2010) doesn't mention the poor basic monitoring of female participation in clinical trials. Only the Office of Research on Women's Health in the United States systematically collects and publishes such data, and its statistics relate solely to publicly funded research.

The research community needs to be able to access participation data easily so that nuanced analysis of inclusion patterns can be conducted — for example, to take account of the proportion of women in non-sex-specific research. A simple solution would be for clinical-trials registries to collect data on the sex of participants.