A mother's instinct is to protect her children at any cost. In the budding yeast Saccharomyces cerevisiae this 'maternal instinct' comes at a high price — accelerated ageing and premature death.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Steinkraus, K. A., Kaeberlein, M. & Kennedy, B. Annu. Rev. Cell Dev. Biol. doi:10.1146/annurev.cellbio.23.090506.123509 (2008).
Egilmez, N. K. & Jazwinski, S. M. J. Bacteriol. 171, 37–42 (1989).
Kennedy, B. K., Austriaco, N. R. Jr & Guarente, L. J. Cell Biol. 127, 1985–1993 (1994).
Shcheprova, Z., Baldi, S., Buvelot Frei, S., Gonnet, G. & Barral, Y. Nature 454, 728–734 (2008).
Sinclair, D. A. & Guarente, L. Cell 91, 1033–1042 (1997).
Aguilaniu, H. et al. Science 299, 1751–1753 (2003).
Erjavec, N., Larsson, L., Grantham, J. & Nyström, T. Genes Dev. 21, 2410–2421 (2007).
Lai, C.-Y., Jaruga, E., Borghouts, C. & Jazwinski, S. M. Genetics 162, 73–87 (2002).
Luedeke, C. et al. J. Cell Biol. 169, 897–908 (2005).
Smith, E. D. et al. Genome Res. 18, 564–570 (2008).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kaeberlein, M. A molecular age barrier. Nature 454, 709–710 (2008). https://doi.org/10.1038/454709a
Published:
Issue Date:
DOI: https://doi.org/10.1038/454709a
