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Transcriptional pharmacology of neurodegenerative disorders: novel venue towards neuroprotection against excitotoxicity?

Abstract

Transcription factors NF-κB/Rel represent the point of convergence of several signalling pathways relevant to neurodegeneration. The finding that salicylates elicit neuroprotection via blockade of NF-κB provides new opportunities for pharmacological intervention.

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Grilli, M., Memo, M. Transcriptional pharmacology of neurodegenerative disorders: novel venue towards neuroprotection against excitotoxicity?. Mol Psychiatry 2, 192–194 (1997). https://doi.org/10.1038/sj.mp.4000252

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  • DOI: https://doi.org/10.1038/sj.mp.4000252

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