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Disruption of orientation tuning visual cortex by artificially correlated neuronal activity

Nature volume 386, pages 680–685 (1997)Cite this article

Abstract

In the primary visual cortex, the development of orientation selectivity is influenced by patterns of neural activity. The introduction of artificially correlated activity into the visual pathway (through synchronous activation of retinal ganglion cell axons in the optic nerve) substantially weakens the orientation selectivity of neurons in superficial and deep cortical layers. This is consistent with activity having an instructive role in shaping cortical neuron receptive field tuning properties.

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Authors and Affiliations

  1. Howard Hughes Medical Institute and Department of Neurobiology, Duke University School of Medicine, Durham, North Carolina, 27710, USA

    Michael Weliky & Lawrence C. Katz

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  1. Michael Weliky
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  2. Lawrence C. Katz
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Weliky, M., Katz, L. Disruption of orientation tuning visual cortex by artificially correlated neuronal activity. Nature 386, 680–685 (1997). https://doi.org/10.1038/386680a0

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