In the embryo, cells have to be aware of where they are so that they can differentiate into the right tissue. In part, long-range signalling is involved, but it is not yet clear how diffusible morphogens specify cell type.
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Smith, J. How to tell a cell where it is. Nature 381, 367–368 (1996). https://doi.org/10.1038/381367a0
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DOI: https://doi.org/10.1038/381367a0
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