The RNA-processing enzyme MRP contains an RNA component that is essential for its activity. Unexpectedly, it seems that mutations in the gene encoding this RNA cause a multifaceted human disease.
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RNase MRP and the RNA processing cascade in the eukaryotic ancestor
BMC Evolutionary Biology Open Access 08 February 2007
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Clayton, D. A big development for a small RNA. Nature 410, 29–31 (2001). https://doi.org/10.1038/35065191
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DOI: https://doi.org/10.1038/35065191
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