The long incubation period between infection and the development of clinical AIDS may be due to an immune response to the initial infection which persists with health and wanes with disease. If this response can be boosted, it may be possible to reduce the viral burden, prevent the development of disease and reduce contagiousness.
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Salk, J. Prospects for the control of AIDS by immunizing seropositive individuals. Nature 327, 473–476 (1987). https://doi.org/10.1038/327473a0
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DOI: https://doi.org/10.1038/327473a0
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