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T-cell receptor: The present state of recognition

The long pursuit of the genes encoding the antigen receptor of T lymphocytes ended last year with the isolation of three genes — the expected α and β genes and a third gene, γ, which was entirely unexpected. Now that more is known about these and other related genes, how much more do we understand about the mechanism of antigen recognition by T cells and the molecular basis of cellular immunity?

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Robertson, M. T-cell receptor: The present state of recognition. Nature 317, 768–771 (1985). https://doi.org/10.1038/317768a0

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