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A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro

Abstract

Stimulation of in vitro transcription by the simian virus 40 enhancer involves a rapid and stable binding of a trans-acting factor with both the 5′- and 3′-domains of the enhancer sequence. The enhancer factor, which differs from other types of transcriptional factors, can interact with other enhancer elements.

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Sassone-Corsi, P., Wildeman, A. & Chambon, P. A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro. Nature 313, 458–463 (1985). https://doi.org/10.1038/313458a0

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