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Cell type-specific activation of actin genes in the early amphibian embryo

Nature volume 311, pages 716–721 (1984)Cite this article

Abstract

Muscle actin genes are the earliest yet described to show cell type-specific activation in amphibian embryos. Gene-specific probes show that α-skeletal and α-cardiac actin genes start to be transcribed simultaneously at the end of gastrulation, but only in those regions of the mesoderm that subsequently form embryonic muscle. Their expression provides a molecular marker for early cell determination.

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Authors and Affiliations

  1. CRC Molecular Embryology Research Group, Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, UK

    T. J. Mohun, S. Brennan, N. Dathan, S. Fairman & J. B. Gurdon

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  1. T. J. Mohun
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  2. S. Brennan
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  3. N. Dathan
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  4. S. Fairman
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  5. J. B. Gurdon
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Mohun, T., Brennan, S., Dathan, N. et al. Cell type-specific activation of actin genes in the early amphibian embryo. Nature 311, 716–721 (1984). https://doi.org/10.1038/311716a0

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