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A transposon in Streptococcus faecalis with fertility properties

Abstract

Certain strains of streptococci have been shown to be capable of conjugatively transferring drug resistance determinants in the apparent absence of plasmid DNA1–6. The transferrable tetracycline resistance (Tcr) marker of Streptococcus faecalis DS16 has been located on a transposon, designated Tn 9162,4,7. We show here that when chromosomal Tn 916 is conjugatively transferred it inserts into a number of different sites on the recipient chromosome. Our studies also imply that transfer and transposition share a common step, which may be excision of the transposon from the donor chromosome.

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Gawron-Burke, C., Clewell, D. A transposon in Streptococcus faecalis with fertility properties. Nature 300, 281–284 (1982). https://doi.org/10.1038/300281a0

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