Abstract
The viruses causing the recent outbreaks of foot and mouth disease in the United Kingdom (Jersey and the Isle of Wight) and France (Brittany and Normandy) have been shown by analysis of the virus-induced proteins and the viral RNAs to be closely related to each other, and to another virus of serotype O, Lausanne 1965 (Switzerland), which is used in the preparation of commercial vaccines. Comparative studies described here and elsewhere1,2 indicate that foot and mouth disease virus (FMDV) is extremely unlikely to survive unaltered in the field for 16 yr. Thus the outbreaks must have been caused by the re-introduction into the field of the Lausanne strain, possibly by escape from a laboratory, by the use of a vaccine contaminated with the virus or by an incompletely inactivated foot and mouth disease vaccine.
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King, A., Underwood, B., McCahon, D. et al. Biochemical identification of viruses causing the 1981 outbreaks of foot and mouth disease in the UK. Nature 293, 479–480 (1981). https://doi.org/10.1038/293479a0
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DOI: https://doi.org/10.1038/293479a0
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