Abstract
It has recently been suggested that the endogenous retroviruses present in many different species might be involved during stimulation of the immune system of their hosts1–3. We have now studied the expression of two avian retroviral antigens p27 and gp85 in chicken lymphoid cells by indirect immunofluorescence (IIF) and by complement-dependent microcytotoxicity (CDM). We have now found that these viral antigens are expressed in peripheral blood leukocytes of adults and embryos and in splenic and bursal lymphocytes of Spafas gs− chf− chickens but they are not expressed in fibroblasts cultured from the feather follicles of the same individual adult birds nor in fibroblasts cultured from embryos of the same flock. The differential expression of viral antigens in leukocytes may be related to a specific property or function of these cells.
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Jurdic, P., Huppert, J., Greenland, T. et al. Retroviral antigens on gs− chf− leukocytes. Nature 288, 400–401 (1980). https://doi.org/10.1038/288400a0
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DOI: https://doi.org/10.1038/288400a0
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