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Ogston and the development of prochirality theory

Abstract

Ogston's explanation for differentiation of identical groups in symmetrical compounds led to the important stereochemical concept of prochirality, which in turn, has made significant contributions to the understanding of enzyme reaction mechanisms.

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Bentley, R. Ogston and the development of prochirality theory. Nature 276, 673–676 (1978). https://doi.org/10.1038/276673a0

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