Abstract
INCREASED glucose concentration in the medium in which normal fibroblasts are grown in culture caused an increase in one type of procollagen synthesised, an increase in the incorporation of labelled carbon from glucose into collagen, and an increase in the rate of collagen secretion. The addition of insulin to the culture media did not affect collagen secretion.
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VILLEE, D., POWERS, M. Effect of glucose and insulin on collagen secretion by human skin fibroblasts in vitro. Nature 268, 156–158 (1977). https://doi.org/10.1038/268156a0
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DOI: https://doi.org/10.1038/268156a0
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