Abstract
BIOLOGICAL phenomena are highly specific1–4 and much effort has been devoted to establishing the relationship between biological activity and molecular shape. We report here the sharp dependence of selectivity in the oxidation of a pair of thiols on their structures or on environment, the mode of each dependence of selectivity being controlled dominantly by their tendency towards intermolecular association.
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ENDO, T., KUWAHARA, A., TASAI, H. et al. Intermolecular association and geometrical shape as two factors controlling chemical reactions. Nature 268, 74–76 (1977). https://doi.org/10.1038/268074a0
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DOI: https://doi.org/10.1038/268074a0
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