Abstract
IT would be useful to find out whether a particular part of the chromosome set in the living cell can be labelled so that the labelled and unlabelled chromosomes can be clearly distinguished. This would make it possible to determine the localisation of chromosomes during interphase when the chromosomes are dispersed as tangled thin threads which cannot be traced with the light or electron microscope. We have suggested1 that an ultraviolet microbeam can be used to provoke the labelling of part of a chromosome set with 3H-thymidine (3H-TdR). Here we present data on mammalian cell labelling following ultraviolet microirradiation which are consistent with this suggestion.
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SAKHAROV, V., VORONKOVA, L., PYRUZYAN, L. et al. Partial chromosomal set labelling induced by ultraviolet microbeam irradiation of mitotic cells. Nature 260, 784–785 (1976). https://doi.org/10.1038/260784a0
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DOI: https://doi.org/10.1038/260784a0
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