Abstract
SOLUBLE complexes composed of protein antigenically related to fibrinogen have been found in the plasma of patients suffering from thrombosis or a hypercoagulable state1. These complexes are important as they could provide a sensitive method for the laboratory diagnosis of such conditions at a very early stage in their development1. Little is known concerning the structure, formation and breakdown of soluble complexes in vivo.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Fletcher, A. P., Alkjaersig, N., O'Brien, J., Tulevski, V. G., Trans. Ass. Am. Phys., 83, 159–166 (1970).
Bang, N. U., et al., Ser. Haemat., 6, 494–512 (1973).
Asbeck, F., Lechler, E., Martin, M., and van de Loo, J., Haemostasis (in the press).
Holleman, W. H., and Coen, L. J., Biochim. biophys. Acta, 200, 587–589 (1970).
Pitney, W. R., Bell, W. R., and Bolton, G., Br. J. Haemat., 16, 165–171 (1969).
Vermylen, J., Donati, M. B., and Verstraete, M., Scand. J. Haemat., Suppl., 13, 219–223 (1970).
von Hugo, R., and Graeff, H., Thromb. Diath. haemorrh., 29, 122–129 (1973).
Mancini, G., Carbonara, A. O., and Heremans, J. F., Immunochemistry, 2, 235–254 (1965).
Weber, K., and Osborn, M., J. biol. Chem., 244, 4406–4412 (1969).
Mattock, P., and Esnouf, M. P., Nature new Biol., 233, 277–279 (1971).
Konttinen, Y. P., Lalla, M. L. T., and Turunen, O., Thromb. Diath. haemorrh., 30, 403–413 (1973).
Gaffney, P. J., and Brasher, M., Nature, 251, 53–54 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MCKILLOP, C., EDGAR, W., FORBES, C. et al. Possible pathway for formation of fibrin degradation products during ancrod therapy. Nature 255, 638–640 (1975). https://doi.org/10.1038/255638a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/255638a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
