Abstract
WE describe an improved alogrithm (EFIRT) for solving iteratively the linear equations relating a three-dimensional density to a given set of its projections, when the unknown density is expressed as samples on a grid. The need to solve such equations arises in electron microscopy, medical radiography, radio and X-ray astronomy and other fields. The projection equations comprise a very large, sparse and often under-determined set. If the number of unknowns is not too large, the equations may be solved by a least squares procedure, using filtering to combat the ill-conditioning1. The number of unknowns is often too great for such a procedure to be computationally feasible and iterative techniques2,3 must be used. Alternatively the Fourier transform provides a stable and computationally efficient means of solution1. Sometimes use of the Fourier transform is not convenient; for example, if point rather than plane projections are given or if the projection data are weighted by a non-uniform but linear response of the measuring device. Such problems are much more readily expressed in terms of projection equations and the development of stable methods for their solution is therefore important.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Crowther, R. A., DeRosier, D. J., and Klug, A., Proc. R. Soc., A 317, 319–340 (1970).
Gordon, R., Bender, R., and Herman, G. T., J. theoret. Biol., 29, 471–481 (1970).
Gilbert, P., J. theoret. Biol., 36, 105–117 (1972).
Herman, G. T., and Rowland, S., Proc. Twelfth Annual San Diego Biochemical Symposium (in the press).
Klug, A., and Crowther, R. A., Nature, 238, 435–440 (1972).
Bracewell, R. N., and Riddle, A. C., Astrophys. J., 150, 427–434 (1967).
Gilbert, P., Proc. R. Soc. Lond., B 182, 89–102 (1972).
Smith, P. R., Peters, T. M., and Bates, R. H. T., J. Phys. A, 6, 361–382 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CROWTHER, R., KLUG, A. Three dimensional image reconstruction on an extended field—a fast, stable algorithm. Nature 251, 490–492 (1974). https://doi.org/10.1038/251490a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/251490a0
This article is cited by
-
Experimental measurement of impulse response and noise for an emission computed tomography system
European Journal of Nuclear Medicine (1979)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.