Abstract
ELECTRIC potentials generated by the inner ear in response to sound stimulation were first recorded 40 yr ago1. Studies of these extracellular potentials have led to hypotheses about the role of intracellular potentials in sensory transduction in receptor (hair) cells2,3. It is difficult, however, to infer these intracellular potentials from extracellular measurements alone4–7; measurements of intracellular potentials from hair cells are clearly desirable. Although intracellular potentials in other hair-cell receptors have been reported recently8,9, the few previous attempts to record such potentials in the cochlea have not yielded significant results10. We report here intracellular responses from single hair cells and supporting cells in the cochlea of the alligator lizard Gerrhonotus multicarinatus.
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References
Wever, E. G., and Bray, C. W., Proc. natn. Acad. Sci. U.S.A., 16, 344 (1930).
Davis, H., Physiol. Rev., 37, 1 (1957).
Flock, Å., in Handbook of sensory physiology, 1 (edit. by Loewenstein, W. R.), 396 (Springer, New York, 1971).
Békésy, G., J. acoust. Soc. Am., 23, 18 (1951).
Whitfield, I. C., and Ross, H. F., J. acoust. Soc. Am., 38, 126 (1965).
Kohllöffel, L. U. E., Acta otolaryngol., Suppl., 288 (1971).
Weiss, T. F., Peake, W. T., and Sohmer, H. S., J. acoust. Soc. Am., 50, 602 (1971).
Harris, G. G., Frishkopf, L. S., and Flock, Å., Science, 167, 76 (1970).
Flock, Å., Jørgensen, M., and Russell, I. J., in Basic mechanisms in hearing (edit. by Møller, A. R.), 273 (Academic Press, New York, 1973).
Fex, J., in Handbook of sensory physiology (edit. by Keidel, W. D., and Neff, W. D.), 5 (Springer, New York, in the press).
Retzius, G., Das gehörorgan de wirbelthiere, 2 (Samson and Wallin, Stockholm, 1884).
Romer, A. S., The vertebrate body, 525 (Saunders, Philadelphia and London, 1946).
Baird, I., in Biology of the reptilia (edit. by Gans, C., and Parsons, T. S.), 2, 193 (Academic Press, New York, 1970).
Shute, C. C. D., and Bellairs, A. d'A., Proc. zool. Soc. Lond., 123, 695 (1953).
Gilad, P., Shtrikman, S., Hillman, P., Rubinstein, M., and Eviatar, A., J. acoust. Soc. Am., 41, 1232 (1967).
Potter, D. D., Furshpan, E. J., and Lennox, E. S., Proc natn Acad. Sci. U.S.A., 55, 328 (1966).
Stretton, A. O. W., and Kravitz, E. A., Science, 162, 132 (1968).
Dallos, P., The auditory periphery (Academic Press, New York, 1973).
Weiss, T. F., Mulroy, M. J., and Altmann, D. W., J. acoust. Soc. Am., 55, 606 (1974).
Liley, A. W., J. Physiol., 134, 427 (1956).
Katz, B., Proc. R. Soc., B 155, 455 (1962).
Tasaki, I., J. Neurophysiol., 17, 97 (1954).
Kiang, N. Y. S., Watanabe, T., Thomas, E. C., and Clark, L. F., Discharge patterns of single fibres in the cat's auditory nerve (MIT Press, Cambridge, 1965).
Wever, E. G., J. aud. Res., 5, 331 (1965).
Wever, E. G., J. aud. Res., 11, 160 (1971).
Mulroy, M. J., Dissertation, Univ. California, San Francisco 1968.
Sohmer, H. S., Peake, W. T., and Weiss, T. F., J. acoust. Soc. Am., 50, 572 (1971).
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MULROY, M., ALTMANN, D., WEISS, T. et al. Intracellular electric responses to sound in a vertebrate cochlea. Nature 249, 482–485 (1974). https://doi.org/10.1038/249482a0
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DOI: https://doi.org/10.1038/249482a0
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