Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Immunological detection of antigen(s) associated with rat colon carcinoma

Abstract

CANCER of the colon and rectum is exceeded only by cancer of the lung as a cause of cancer death in the United States. Of the approximately 350,000 deaths from cancer in 1973, 47,400 were from cancer of the colon and rectum; of the approximately 665,000 cancers diagnosed in 1973, 79,000 were in the colon and rectum. Denmark, Great Britian, Ireland, Canada, New Zealand, Australia, Belgium and Austria have equally high or even slightly higher death rates from this disease and it is a significant cause of morbidity and mortality in most western countries. Improved surgical techniques and the development of new diagnostic methods have not significantly affected these mortality statistics1.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Silverberg, E., and Holleb, A. I., Ca.- A Cancer for Clinicians, 23, 2–23 (1973).

    Article  Google Scholar 

  2. Druckey, H., in Carcinoma of the colon, and antecedent epithelium (edit. by Burdette, W. J.), 267 (Thomas, Springfield, Illinois, 1970).

    Google Scholar 

  3. Rogers, A. E., Herndon, B. J., and Newberne, P. M., Cancer Res., 33, 1003 (1973).

    CAS  PubMed  Google Scholar 

  4. Rogers, A. E., and Newberne, P. M., Nature 246, 491 (1973).

    Article  ADS  CAS  Google Scholar 

  5. Newberne, P. M., and Rogers, A. E., J. natn. Cancer Inst., 50, 439 (1973).

    Article  CAS  Google Scholar 

  6. Gold, P.,and Freedman, S. O., J. expl. Med., 122, 467 (1965).

    Article  CAS  Google Scholar 

  7. Thomson, D. M., Krupey, J., Freeman, S. O., Gold, P., Proc. Nat. Acad. Sci. U.S.A., 64, 161 (1969).

    Article  ADS  CAS  Google Scholar 

  8. Lo Gerfo, P., Krupey, J., Hansen, H. J., New Engl. J. Med., 285, 138 (1971).

    Article  CAS  Google Scholar 

  9. Zamcheck, N., Moore, T. L., Dhar, P., and Kupchik, H. Z., New Engl. J. Med., 286, 83 (1972).

    Article  CAS  Google Scholar 

  10. Saravis, C. A., Kupchik, H. Z., and Zamcheck, N., Immun. Comm., 1, 395 (1973).

    Article  Google Scholar 

  11. Kroes, R. M., Sontag, J. M., Weisburger, J. H., Newberne, P. M., and Wogan, G. N., Nature, 240, 240 (1972).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

GARMAISE, AK., ROGERS, A., NEWBERNE, P. et al. Immunological detection of antigen(s) associated with rat colon carcinoma. Nature 248, 706–707 (1974). https://doi.org/10.1038/248706a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/248706a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing