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Early changes in the kidneys of BALB/c mice infected with lactic dehydrogenase virus

Nature volume 248, pages 686–687 (1974)Cite this article

Abstract

MICE infected with lactic dehydrogenase virus (LDV) have lifelong viraemia and raised plasma enzyme levels1–4. In spite of rapid and prolonged virus replication, probably in the macrophages, only minor histological changes in lymphoid organs are reported5. Antibodies are produced6 and complexes are said to be deposited in the glomerular capillary walls but only minimal glomerulonephritis results7,8.

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References

  1. Riley, V., Lilly, F., Huerto, E., and Bardell, D., Science, 132, 545 (1960).

    Article  ADS  CAS  Google Scholar 

  2. Mahy, B. W. J., Rowson, K. E. K., Parr, C. W., and Salaman, M. H., J. exp. Med., 122, 967 (1965).

    Article  CAS  Google Scholar 

  3. Mahy, B. W. J., and Rowson, K. E. K., Science, 149, 756 (1965).

    Article  ADS  CAS  Google Scholar 

  4. Mahy, B. W. J., Rowson, K. E. K., and Parr, C. W., J. exp. Med., 125, 277 (1967).

    Article  CAS  Google Scholar 

  5. Snodgrass, M. J., Lowrey, D. S., and Hanna, M. G., J. Immun., 108, 877 (1972).

    CAS  PubMed  Google Scholar 

  6. Rowson, K. E. K., Mahy, B. W. J., and Bendinelli, M., Virology, 28, 775 (1966).

    Article  CAS  Google Scholar 

  7. Porter, D. D., and Porter, H. G., J. Immun., 106, 1264 (1971).

    CAS  PubMed  Google Scholar 

  8. Oldstone, M. B. A., and Dixon, F. J., J. Immun., 106, 1260 (1971).

    CAS  PubMed  Google Scholar 

  9. Oldstone, M. B. A., and Dixon, F. J., Science, 175, 784 (1972).

    Article  ADS  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pathology, The Institute of Laryngology and Otology, 330–332, Gray's Inn Road, London, WC1 8EE

    K. E. K. ROWSON, L. MICHAELS & G. A. HURST

Authors
  1. K. E. K. ROWSON
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  2. L. MICHAELS
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  3. G. A. HURST
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ROWSON, K., MICHAELS, L. & HURST, G. Early changes in the kidneys of BALB/c mice infected with lactic dehydrogenase virus. Nature 248, 686–687 (1974). https://doi.org/10.1038/248686a0

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  • DOI: https://doi.org/10.1038/248686a0

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