Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Lacunae in Erythrocyte Monolayers induced by Adherent Leukocytes

Nature volume 247, pages 57–58 (1974)Cite this article

Abstract

POLYMORPHONUCLEAR leukocytes are capable of migration, aggregation, adherence, and phagocytosis as well as the intracellular destruction of bacteria1. The observations reported here suggest yet another facility, namely that of repulsion. These experiments indicate that surface adherent leukocytes, whether polymorphonuclear or other types, repel erythrocytes from the immediate zone about them, thus creating lacunae.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Bryant, R. E., Des Prez, R. M., Van Way, M. H., and Rogers, D. E., J. exp. Med., 124, 483 (1966).

    Article  CAS  Google Scholar 

  2. Shelley, W. B., Am. J. clin. Path., 39, 433 (1963).

    Article  Google Scholar 

  3. Bessis, M., Cytology of the Blood and Blood-Forming Organs (Grune and Stratton, New York, 1956).

    Google Scholar 

  4. Manley, R. S., Adhesion in Biological Systems (Academic Press, New York, 1970).

    Google Scholar 

  5. Bryant, R. E., and Sutcliffe, M. C., Proc. Soc. biol. Med., 141, 196 (1972).

    Article  CAS  Google Scholar 

  6. Rabinowitz, Y., and Schrek, R., Blood, 20, 453 (1962).

    CAS  PubMed  Google Scholar 

  7. Bessis, M., in The Cell (edit. by Brachet, J., and Mirsky, A. E.), 5, 163 (Academic Press, New York, 1961).

    Google Scholar 

  8. Jerne, N. K., and Nordin, A. A., Science, N.Y., 140, 405 (1963).

    Article  ADS  Google Scholar 

  9. Ingraham, J. S., and Bussard, A., J. exp. Med., 119, 667 (1964).

    Article  CAS  Google Scholar 

  10. Rosenberg, M. D., Biophysical J., 1, 137 (1960).

    Article  ADS  CAS  Google Scholar 

  11. Taylor, A. C., Expl. Cell Res., Suppl. 8, 154 (1961).

  12. Taylor, A. C., in Biological Interactions in Normal and Neoplastic Growth (edit. by Brennan, N. J., and Simpson, W. L.), 169 (Little, Brown, and Co., Boston, 1962).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Dermatology, School of Medicine, University of Pennsylvania, Philadelphia, 19104

    WALTER B. SHELLEY

Authors
  1. WALTER B. SHELLEY
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SHELLEY, W. Lacunae in Erythrocyte Monolayers induced by Adherent Leukocytes. Nature 247, 57–58 (1974). https://doi.org/10.1038/247057a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/247057a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing