Abstract
THE bronchopulmonary system, one of the most important sites of access for antigen into the body, has a highly developed lymphatic system1 and the capacity to effect a local immune response2. Any modification of these defences by the environment is likely to have a lasting influence on the health of an animal. Chronic exposure to sulphur dioxide and carbon has been found to decrease the immune response of mice to inhaled antigen3. Cigarette smokers have also been found to have decreased serum antibody to influenza virus after infection or vaccination4. Both air pollution and cigarette smoking have been associated with an increased susceptibility to respiratory infection5,6.
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THOMAS, W., HOLT, P. & KEAST, D. Effect of Cigarette Smoking on Primary and Secondary Humoral Responses of Mice. Nature 243, 240–241 (1973). https://doi.org/10.1038/243240a0
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DOI: https://doi.org/10.1038/243240a0
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