Abstract
SIMIAN virus SV40, a DNA tumour virus, causes a productive infection in both monkey and human cells, leading to lysis of the cells and release of infectious virus. In murine systems, however, the virus transforms the cells, leading to new virus-specific antigens on the transformed cells1. These transformed cells induce tumours in mice which then respond to the tumour specific antigen2,3. I report here protection of mice by SV40 when given with syngeneic myeloma tumour cells.
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References
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REINISCH, C. SV40 Protection in Myeloma Oncogenesis. Nature 242, 470–471 (1973). https://doi.org/10.1038/242470a0
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DOI: https://doi.org/10.1038/242470a0
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