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Hypotaurine: Regulation of Production in Seminal Vesicles and Prostate of Guinea-pig by Testosterone

Nature volume 241, pages 202–203 (1973)Cite this article

Abstract

THE accessory sex organs of the male are dependent on androgens for their growth, maintenance and secretory activity. These physiological effects are regulated through the RNA-protein biosynthesis system in the various animal species. The protein of the guinea-pig seminal vesicles, seminal fluid and prostates decreases after castration and increases after testosterone administration in direct proportion to the changes in tissue weights without change in amino-acid composition. The rate of incorporation into protein of 2-14C glycine in vivo2 and several 14C amino-acids by cell free preparations of these tissues3 is decreased by castration and increased by testosterone with concomitant changes in RNA4.

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Authors and Affiliations

  1. Laboratory of Experimental Endocrinology, University of Alabama in Birmingham Medical Center, Birmingham, Alabama, 35233

    C. D. KOCHAKIAN

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  1. C. D. KOCHAKIAN
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KOCHAKIAN, C. Hypotaurine: Regulation of Production in Seminal Vesicles and Prostate of Guinea-pig by Testosterone. Nature 241, 202–203 (1973). https://doi.org/10.1038/241202a0

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