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Relation between Prostaglandin E2 and Adrenaline Reversal in the Rat Uterus

Abstract

THE inhibitory response of the rat uterus to adrenaline in the presence of isoprenaline inhibition can be reversed in induced oestrus but not in the progestational state, and it has been postulated that a motor substance accumulates during the isoprenaline inhibition and is released on addition of adrenaline1. The same sequence of events has also been observed when adrenaline was used as the initial inhibitory agent. The motor response to adrenaline is even more readily obtained in the late pregnant uterus but not in dioestrus2.

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TOTHILL, A., RATHBONE, L. & WILLMAN, E. Relation between Prostaglandin E2 and Adrenaline Reversal in the Rat Uterus. Nature 233, 56–57 (1971). https://doi.org/10.1038/233056a0

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  • DOI: https://doi.org/10.1038/233056a0

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