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Corticotrophin Releasing Factor in Hypophysial Portal Blood of Rats

Nature volume 230, pages 467–468 (1971)Cite this article

Abstract

IN spite of the work on factors in brain tissue which seem to release pituitary hormone1, little has been done to determine whether these factors are present in hypophysial portal blood. Early work2 suggested that blood from the empty sella turcica of hypophysectomized dogs can stimulate the release of adrenocorticotrophic hormone (ACTH) and, more recently, it has been shown that there is luteinizing hormone releasing activity in hypophysial portal blood of rats3,4. We have now investigated whether hypophysial portal blood of rats contains a corticotrophin releasing factor (CRF).

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Authors and Affiliations

  1. Department of Anatomy, Monash University, Clayton, 3168, Victoria

    G. FINK, JANICE R. SMITH & J. TIBBALLS

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  1. G. FINK
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  2. JANICE R. SMITH
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  3. J. TIBBALLS
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FINK, G., SMITH, J. & TIBBALLS, J. Corticotrophin Releasing Factor in Hypophysial Portal Blood of Rats. Nature 230, 467–468 (1971). https://doi.org/10.1038/230467a0

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