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Crystallization of a Second Adenovirus Protein (the Fibre)

Nature volume 230, pages 456–457 (1971)Cite this article

Abstract

THE adenovirus capsid has icosahedral symmetry, and is constructed from 252 capsomeres1. In all, 240 hexons define the three-fold and two-fold positions on the faces and edges of the icosahedron, and there are twelve pentons (each consisting of a penton base and a projecting fibre) at the five-fold vertices2,3. Cells infected with adenovirus produce free hexons, pentons and fibres as well as intact virions, and these free “soluble antigens” have been purified by several methods (see review by Schlesinger4). Crystallization of the hexon has already been described5 and we report here a procedure for purification and crystallization of the fibre.

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Authors and Affiliations

  1. Division of Virology, National Institute for Medical Research, Mill Hill, London, NW7

    VIVIEN MAUTNER & H. G. PEREIRA

Authors
  1. VIVIEN MAUTNER
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  2. H. G. PEREIRA
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MAUTNER, V., PEREIRA, H. Crystallization of a Second Adenovirus Protein (the Fibre). Nature 230, 456–457 (1971). https://doi.org/10.1038/230456a0

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