Abstract
SINCE the discovery of methyl mercury formation in lake sediments contaminated with inorganic or phenyl mercury1, there has been a good deal of speculation about the mechanism of this synthesis. One process involving methyl-cobalamin (a B12-derivative) was demonstrated in cell-free extracts of methanogenic bacteria2. Vitamin B12 is not known to be involved in the metabolism of Neurospora3,4, and so we have investigated the biosynthesis of methyl mercury in this organism, where the pathway should be different.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Jensen, S., and Jernelöv, A., Biocidinformation, 10, Nordforsk, May (1967); Jensen, S., and Jernelöv, A., Biocidinformation, 14, Nordforsk, February (1968); Jensen, S., and Jernelöv, A., Nature, 223, 753 (1969).
Wood, J. M., Kennedy, S. F., and Rosén, C. G., Nature, 220, 173 (1968).
Dalal, F. R., Rege, D. V., and Sreenivasan, A., Biochem. J., 81, 317 (1961).
Selhub, J., Burton, E., and Sakami, W., Fed. Proc., 28, 352 (1969).
Metylkvicksilver i fisk, Nordisk Hygienisk Tidskr., Suppl. 3 (1970).
Jernelöv, A., Vatten, 25, 304 (1969).
Miller, M. A., and Harmon, S. A., Nature, 215, 531 (1967).
Fries, N., Symbolae Bot. Upsaliensis, 3, 188 (1938).
Westöö, G., Acta Chem. Scand., 20, 2131 (1966).
Wiebers, J. L., and Garner, H. R., J. Bact., 80, 51 (1960); Wiebers, J. L., and Garner, H. R., Biochim. Biophys. Acta, 117, 403 (1966).
Marzluf, G. A., and Metzenberg, R. L., J. Mol. Biol., 33, 423 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LANDNER, L. Biochemical Model for the Biological Methylation of Mercury suggested from Methylation Studies in vivo with Neurospora crassa. Nature 230, 452–454 (1971). https://doi.org/10.1038/230452a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/230452a0
This article is cited by
-
What did we know and which questions did we ask with regard to environmental contaminants in the early 1970s?
Ambio (2021)
-
Mercury pollution in the coastal Urmia aquifer in northwestern Iran: potential sources, mobility, and toxicity
Environmental Science and Pollution Research (2021)
-
Transgenic merA and merB expression reduces mercury contamination in vegetables and grains grown in mercury-contaminated soil
Plant Cell Reports (2020)
-
Mercury transport and fate in municipal solid waste landfills and its implications
Biogeochemistry (2020)
-
Biotic and Abiotic Degradation of Methylmercury in Aquatic Ecosystems: A Review
Bulletin of Environmental Contamination and Toxicology (2019)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.