Abstract
THE transfer of skeletal muscle fibres from Ringer solution containing 100–200 mM glycerol, urea or other low molecular hydrophilic non-electrolytes to normal Ringer leads to the development of vacuolation clearly visible under the light microscope1. In the case of glycerol efflux, vacuolation develops within a few minutes and persists for several hours, after which fibre structure is gradually restored to normal. Reimmersion of vacuolized fibres in glycerol-Ringer results in a rapid disappearance of vacuoles. The same effect is produced by the influx of some other low molecular non-electrolytes.
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KROLENKO, S. Effect of Fluxes of Sugars and Mineral Ions on the Light Microscopic Structure of Frog Fast Muscle Fibres. Nature 229, 424–426 (1971). https://doi.org/10.1038/229424a0
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DOI: https://doi.org/10.1038/229424a0
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