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Low Molecular Weight Serum Immunoglobulin M in Experimental Trypanosomiasis

Nature volume 228, pages 1208–1210 (1970)Cite this article

Abstract

ANTIGENIC stimulation in different species of lower vertebrates elicits formation of high and low molecular weight antibodies, both belonging to the μ-heavy chain class. In mammals, the occurrence of low molecular weight (LMW) IgM immunoglobulins has been described mainly in man2 affected by various immunological deficiencies, myelomas, collagen diseases3–7 and, in recent years, in trypanosomiasis caused by Trypanosoma gambiense species8.

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Authors and Affiliations

  1. Pediatric Research Laboratories, Variety Club Heart Hospital, University of Minnesota, Minneapolis, 55455

    D. FROMMEL & D. Y. E. PEREY

  2. Department of Biochemistry, University of Dakar, Sénégal

    R. MASSEYEFF

  3. Pediatric Research Laboratories, Variety Club Heart Hospital, University of Minnesota, Minneapolis, 55455

    R. A. GOOD

Authors
  1. D. FROMMEL
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  2. D. Y. E. PEREY
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  3. R. MASSEYEFF
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  4. R. A. GOOD
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FROMMEL, D., PEREY, D., MASSEYEFF, R. et al. Low Molecular Weight Serum Immunoglobulin M in Experimental Trypanosomiasis. Nature 228, 1208–1210 (1970). https://doi.org/10.1038/2281208a0

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