Abstract
THE regulation of liver regeneration after partial hepatectomy is still poorly understood1–3. A specific humoral factor4–7 or growth hormone8–10 was suggested to be the most likely mediator. Also the increase in portal blood flow11 or nervous factors12 as well as others13–15 was postulated but not clearly demonstrated. The data reported here strongly suggest a humoral mechanism.
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SAKAI, A. Humoral Factor Triggering DNA Synthesis after Partial Hepatectomy in the Rat. Nature 228, 1186–1187 (1970). https://doi.org/10.1038/2281186a0
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DOI: https://doi.org/10.1038/2281186a0
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