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In vitro Synthesis of a DNA Dependent RNA Polymerase Coded on Coliphage T7 Genome

Abstract

A system is characterized for synthesizing in vitro the RNA polymerase of phage T7.

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References

  1. Studier, F. W., and Maizel, J. V., Virology, 39, 575 (1969).

    Article  CAS  Google Scholar 

  2. Summers, W. C., and Siegel, R. B., Nature, 223, 1111 (1969).

    Article  ADS  CAS  Google Scholar 

  3. Siegel, R. B., and Summers, W. C., J. Mol. Biol., 49, 115 (1970).

    Article  CAS  Google Scholar 

  4. Chamberlin, M., McGrath, J., and Waskell, L., Nature, 228, 227 (1970).

    Article  ADS  CAS  Google Scholar 

  5. Summers, W. C., and Siegel, R. B., Nature, 228, 1160 (1970).

    Article  ADS  CAS  Google Scholar 

  6. Bryan, R. N., Sugiura, M., and Hayashi, M., Proc. US Nat. Acad. Sci., 62, 483 (1969).

    Article  ADS  CAS  Google Scholar 

  7. Gelfand, D. H., and Hayashi, M., Proc. US Nat. Acad. Sci., 63, 135 (1969).

    Article  ADS  CAS  Google Scholar 

  8. Bryan, R. N., and Hayashi, M., Biochemistry, 9, 1904 (1970).

    Article  CAS  Google Scholar 

  9. Gelfand, D. H., and Hayashi, M., Proc. US Nat. Acad. Sci., 67, 13 (1970).

    Article  ADS  CAS  Google Scholar 

  10. Hayashi, M., Hayashi, M. N., and Hayashi, Y., Cold Spring Harbor Symp. Quant. Biol., 35 (1970, in the press).

  11. Gelfand, D. H., and Hayashi, M., J. Mol. Biol., 44, 501 (1969).

    Article  CAS  Google Scholar 

  12. Ghosh, H. P., Söll, D., and Khorana, H. G., J. Mol. Biol., 25, 275 (1967).

    Article  CAS  Google Scholar 

  13. Roberts, J., Nature, 224, 1168 (1969).

    Article  ADS  CAS  Google Scholar 

  14. Studier, F. W., Virology, 39, 1142 (1969).

    Google Scholar 

  15. Schleif, R., Nature, 223, 1068 (1969).

    Article  ADS  CAS  Google Scholar 

Download references

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GELFAND, D., HAYASHI, M. In vitro Synthesis of a DNA Dependent RNA Polymerase Coded on Coliphage T7 Genome. Nature 228, 1162–1165 (1970). https://doi.org/10.1038/2281162a0

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  • DOI: https://doi.org/10.1038/2281162a0

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