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Mutagenic Methods for determining which DNA Strand is transcribed for Individual Viral Genes

Nature volume 228, pages 54–56 (1970)Cite this article

Abstract

THIS work describes two mutagenic methods for determining which strand of the DNA double helix is transcribed. The approach is applicable to viruses which contain single-stranded DNA in the mature form. The analysis identifies which strand is transcribed for a given viral gene.

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References

  1. Hayashi, M., Hayashi, M. N., and Spiegelman, S., Proc. US Nat. Acad. Sci., 50, 666 (1963).

    Article  ADS  Google Scholar 

  2. Jeng, Y., Gelfand, D., Hayashi, M., Shleser, R., and Tessman, E. S., J. Mol. Biol., 49, 521, (1970).

    Article  CAS  Google Scholar 

  3. Brenner, S., Stretton, A. O. W., and Kaplan, S., Nature, 206, 994 (1965).

    Article  ADS  CAS  Google Scholar 

  4. Tessman, I., Poddar, R. K., and Kumar, S., J. Mol. Biol., 9, 352 (1964).

    Article  CAS  Google Scholar 

  5. Brenner, S., Barnett, L., Katz, E. R., and Crick, F. H. C., Nature, 213, 449 (1967).

    Article  ADS  CAS  Google Scholar 

  6. Vanderbilt, A. S., and Tessman, I., Genetics, 61, s60 (1969).

    Google Scholar 

  7. Tessman, I., Kumar, S., and Tessman, E. S., Science, 158, 267 (1967).

    Article  ADS  CAS  Google Scholar 

  8. McClain, W. H., jun., thesis, Purdue Univ. (1968).

  9. Bockrath, R. C., Osborn, M., and Person, S., J. Bacteriol., 96, 146 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Tessman, E. S., Virology, 25, 303 (1965).

    Article  CAS  Google Scholar 

  11. Howard, B. D., and Tessman, I., J. Mol. Biol., 9, 364 (1964).

    Article  CAS  Google Scholar 

Download references

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Author notes

  1. IRWIN TESSMAN

    Present address: Department of Molecular Biology and Biochemistry, University of California, Irvine, California

Authors and Affiliations

  1. Department of Biological Sciences, Purdue University, Lafayette, Indiana

    ANNE S. VANDERBILT & IRWIN TESSMAN

Authors
  1. ANNE S. VANDERBILT
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  2. IRWIN TESSMAN
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VANDERBILT, A., TESSMAN, I. Mutagenic Methods for determining which DNA Strand is transcribed for Individual Viral Genes. Nature 228, 54–56 (1970). https://doi.org/10.1038/228054a0

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