Abstract
WE wish to describe synergism between two distinct populations of cells in the production of cellular immunity. Much work has concerned these cell types, particularly in relation to humoral immunity, and we shall first distinguish them. Both cell populations originate in the bone marrow. One type migrates to the thymus where it acquires special properties1,2; while there it is referred to as a thymocyte, but it may join the peripheral circulation and is then called a thymus-derived lymphocyte (TDL)3,4. The other type, the bone marrow-derived cell (BMDC), leaves the marrow to populate lymphoid organs or join the circulation, but does not pass through the thymus1–4.
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BARCHILON, J., GERSHON, R. Synergism between Thymocytes and Bone Marrow Cells in a Graft versus Host Reaction. Nature 227, 71–72 (1970). https://doi.org/10.1038/227071a0
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DOI: https://doi.org/10.1038/227071a0
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