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New Mechanism for the Control of Cellular Reactions: the Biochemical Flip-flop

Abstract

IN a complex biological interaction, of the enzyme–substrate type, the enzyme may be considered to be formally analogous to a quantum “measuring apparatus” and the substrate to a collection of observables which characterize the substrate. When a “perturbation” is induced in such a system, the “perturbed” values of the substrate observables will be recorded by the respective “measuring apparatus”. Thus a new type of interaction may be formally derived: the interaction between a “perturbed” substrate, S*, and the corresponding unperturbed enzyme1.

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References

  1. Comorosan, S., Enzymologia, 35, 117 (1968).

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  2. Rosen, R., Bull. Math. Biophys., 30, 481 (1968).

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  3. Comorosan, S., and Murgoci, P., Bull. Math. Biophys., 31, 623 (1969).

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  4. Comorosan, S., Vieru, S., and Sandru, D., Intern. J. Rad. Biol., 17, 105 (1970).

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COMOROSAN, S. New Mechanism for the Control of Cellular Reactions: the Biochemical Flip-flop. Nature 227, 64–65 (1970). https://doi.org/10.1038/227064a0

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