Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Glucose-6-phosphate Dehydrogenase Isoenzymes in Blood Cells

Abstract

THE enzyme glucose-6-phosphate dehydrogenase (G-6-PD) exists in several different forms (isoenzymes) in the human erythrocyte, each apparently determined by a different allele at a single locus on the X chromosome. The structural differences between the isoenzymes lead to different enzymatic activities and often render them separable by gel electrophoresis.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Piomelli, S., Corash, L. M., Davenport, D., Miraglia, J., and Amorisi, E. L., J. Clin. Invest., 47, 940 (1968).

    Article  CAS  Google Scholar 

  2. Rozenszajn, L. A., Epstein, Y., Shoham, D., and Arber, I., J. Lab. Clin. Med., 72, 786 (1968).

    CAS  PubMed  Google Scholar 

  3. Danon, D., and Marikovsky, Y., J. Lab. Clin. Med., 64, 668 (1964).

    CAS  PubMed  Google Scholar 

  4. Davis, B. J., Ann. NY Acad. Sci., 121, 404 (1964).

    Article  CAS  ADS  Google Scholar 

  5. Hori, S. H., Tsutomu, K., and Matsui, S., J. Histochem. Cytochem., 15, 419 (1967).

    Article  CAS  Google Scholar 

  6. Brok, F., Ramot, B., Zwang, E., and Danon, D., Israel J. Med. Sci., 2, 291 (1966).

    CAS  PubMed  Google Scholar 

  7. Kirkman, H. N., and Hann, J. E., Ann. NY Acad. Sci., 151, 133 (1968).

    Article  CAS  ADS  Google Scholar 

  8. Yoshida, A., Hereditary Disorders of Erythrocyte Metabolism, 146 (Grune and Stratton, New York, 1968).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ROZENSZAJN, L., KOLMAN, S., SHOHAM, D. et al. Glucose-6-phosphate Dehydrogenase Isoenzymes in Blood Cells. Nature 226, 862–863 (1970). https://doi.org/10.1038/226862a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/226862a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing