Abstract
THE action of bile salts on the intestinal absorption of fat is well known1 although their role on the transport of water soluble substrates remains poorly defined. Inhibition of monosaccharide transport by both unconjugated and conjugated bile salts has been reported2,3. Pope and co-workers, however, using highly purified preparations of bile salts in jejunal loops from normal rats, concluded that conjugated bile salts have no physiological action on the absorption of glucose in normal animals5. We have reassessed this problem in bile depleted rats using extracorporeally perfused segments of rat jejunum removed with their intact circulation.
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ROY, C., DUBOIS, R. & PHILIPPON, F. Inhibition by Bile Salts of the Jejunal Transport of 3-O-Methyl Glucose. Nature 225, 1055–1056 (1970). https://doi.org/10.1038/2251055a0
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DOI: https://doi.org/10.1038/2251055a0
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