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Uniquely Oriented Epidermal Lipid

Abstract

AN important function of the stratum corneum of skin is to limit the penetration of substances1. This is dependent on a lipid-protein complex which can be disrupted by a variety of polar organic solvents2, and diffusion studies suggest that filamentous protein and certain polar lipids are involved3. We describe here a lipid which has a characteristic orientation with respect to the long axis of the keratin filaments and which may be an important component of the lipid-protein complex.

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References

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GOLDSMITH, L., BADEN, H. Uniquely Oriented Epidermal Lipid. Nature 225, 1052–1053 (1970). https://doi.org/10.1038/2251052a0

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