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Prolactin changes Cholesterol Stores in the Mouse Testis

Abstract

A SERIES of experiments concerned with the influence of prolactin on spermatogenesis and on the accessory reproductive structures in mice led to the suggestion that prolactin can stimulate the production of testicular androgens1. In the female, prolactin is known to affect the synthesis of ovarian steroid hormones; its luteotropic action in the mouse and the rat is particularly well established. The results obtained in the rat2,3, the rabbit4 and in the perfused bovine ovary5 indicate that the prolactin effects on ovarian steroidogenesis may be mediated, at least in part, by changes in cholesterol storage and perhaps discharge. The present work investigates the influence of prolactin on cholesterol stores in the mouse testis.

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References

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BARTKE, A. Prolactin changes Cholesterol Stores in the Mouse Testis. Nature 224, 700–701 (1969). https://doi.org/10.1038/224700a0

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