Abstract
VARIATION in T-maze learning in mice is determined by genetic and environmental (treatment) effects and interactions among them1–4. Lysergic acid diethylamide-25 (LSD-25) affects attack and inhibition behaviour, gross locomotor activity and swimming time in a water T-maze5–7. Strain differences in aggressive behaviour reaction to LSD, that is to say, a genotype × treatment interaction, have been suggested5. Here we evaluate the effect of LSD-25 and genotype on T-maze learning and demonstrate a significant genotype × treatment interaction for some components.
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STASIK, J., KIDWELL, J. Genotype, LSD and T-maze Learning in Mice. Nature 224, 1224–1225 (1969). https://doi.org/10.1038/2241224a0
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DOI: https://doi.org/10.1038/2241224a0
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